Concordance between the TIRADS ultrasound criteria and the BETHESDA cytology criteria on the nontoxic thyroid nodule

Table 6 Heterogeneity assessment by stratifying the variables according to: thyroid cancer family history, accelerated growth of the nodules, firm nodule, underlying structure, vocal chords paralysis, origins, and history of radiation

Strata	Observed Agreement	Expected Agreement	Kappa	Standard Error	95% CI
Thyroid Cancer Family history
Yes	87.98%	60.71%	0.694	0.086	0.53–0.86
No	86.83%	58.81%	0.680	0.066	0.55–0.81
Accelerated Growth of the nodule
Yes	90.40%	60.12%	0.759	0.090	0.58–0.94
No	85.67%	59.89%	0.643	0.065	0.52–0.77
Firm Nodule
Yes	86.82%	58.55%	0.682	0.076	0.53–0.83
No	87.59%	60.10%	0.689	0.073	0.55–0.83
Adjacent Structure Attachment
Yes	94.00%	65.52%	0.826	0.096	0.64–1.01
No	84.62%	59.42%	0.621	0.062	0.50–0.74
Vocal Chords Paralysis
Yes	94.67%	66.11%	0.843	0.096	0.65–1.03
No	84.36%	58.52%	0.623	0.062	0.50–0.74
Origin
Urban (exclusive)	88.70%	58.99%	0.7245	0.065	0.60–0.85
Urban or Rural	84.41%	58.26%	0.6265	0.0881	0.45–0.8
Head and neck radiation therapy
Yes	96.08%	61.48%	0.8982	0.1689	0.57–1.23
No	86.30%	58.55%	0.6695	0.0557	0.56–0.78

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